Britain is to discuss what help it can provide to Turkey in dealing with the mining disaster which has killed at least 245 workers, William Hague said.
The Foreign Secretary will talk with his Turkish counterpart in London tomorrow, where he is attending international talks on Syria.
A desperate hunt is under way for up to 120 miners who remain unaccounted for in the country's worst such disaster.
Violent anti-government protests have broken out in the town of Soma where an explosion caused a pit to collapse.
Mr Hague said: "I was deeply saddened to hear the news of the mining disaster in Soma, Turkey.
"My thoughts and sympathies are with all those who are missing, their families, and also the rescue workers working tirelessly to search for survivors of this tragedy.
"The UK stands ready to support Turkey should assistance be required, and I shall discuss this with Turkish foreign minister (Ahmet) Davutoglu at tomorrow's London meeting on Syria."