Cannabis 'could cut tumour growth'

Hillingdon Times: An ingredient in cannabis could help reduce tumour growth, scientists say An ingredient in cannabis could help reduce tumour growth, scientists say

Cannabis could be used to reduce tumour growth in cancer patients, scientists have said.

New research reveals the drug's main psychoactive ingredient - tetrahydrocannabino (THC) - could be responsible for its success in shrinking tumours.

It is hoped that the findings could help develop a synthetic equivalent with anti-cancer properties.

But researchers warned that cancer sufferers should not be tempted to self-medicate.

Dr Peter McCormick, from the University of East Anglia's (UEA) school of pharmacy, said THC's anti-cancer properties have been known for some time but the study had identified the receptors responsible for fighting tumours.

He added: "Our findings help explain some of the well-known but still poorly understood effects of THC at low and high doses on tumour growth.

"There has been a great deal of interest in understanding the molecular mechanisms behind how marijuana, and specifically THC, influence cancer pathology.

"There has also been a drive in the pharmaceutical industry to create synthetic equivalents that might have anti-cancer properties.

"By identifying the receptors involved we have provided an important step towards the future development of therapeutics that can take advantage of the interactions we have discovered to reduce tumour growth."

The research, carried out with the Universidad Complutense de Madrid in Spain, used samples of human breast cancer cells to induce tumours in mice.

They then targeted the tumours with doses of the cannabis compound and found that two cell receptors in particular were responsible for the drug's anti-tumour effects.

Dr McCormick said: "Our research uses an isolated chemical compound and using the correct concentration is vital.

"Cancer patients should not use cannabis to self-medicate, but I hope that our research will lead to a safe synthetic equivalent being available in the future."

Comments (4)

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11:54pm Tue 15 Jul 14

Clark420 says...

"cancer patients should just lie down and die until we can make profit from synthetic cannabis"
"cancer patients should just lie down and die until we can make profit from synthetic cannabis" Clark420
  • Score: -1

2:19am Mon 21 Jul 14

TaraSam says...

There is no doubt! and it's not exactly THC researchers have now found that the compound, called cannabidiol is key factor in curing cancer with a very high success rate.
http://www.trueactiv
ist.com/there-is-no-
mistaking-the-eviden
ce-cannabis-cures-ca
ncer/
There is no doubt! and it's not exactly THC researchers have now found that the compound, called cannabidiol is key factor in curing cancer with a very high success rate. http://www.trueactiv ist.com/there-is-no- mistaking-the-eviden ce-cannabis-cures-ca ncer/ TaraSam
  • Score: -1

2:27am Mon 21 Jul 14

TaraSam says...

"Cancer patients should not use cannabis to self-medicate, but I hope that our research will lead to a safe synthetic equivalent being available in the future." (Very misleading report)
There is no safer drug than cannabis oil for medication purposes and synthetic THC is not as successful, Big Pharma are desperate not to lose profit of which 80% is in cancer cures with low success rates I may add. Please do the research you could well save somebodies life.
"Cancer patients should not use cannabis to self-medicate, but I hope that our research will lead to a safe synthetic equivalent being available in the future." (Very misleading report) There is no safer drug than cannabis oil for medication purposes and synthetic THC is not as successful, Big Pharma are desperate not to lose profit of which 80% is in cancer cures with low success rates I may add. Please do the research you could well save somebodies life. TaraSam
  • Score: -1

12:43am Fri 25 Jul 14

Dr Martin says...

""There is some evidence that cannabis or cannabis derivatives might help with cancer symptoms and treatment side effects, for example, sickness caused by chemotherapy. However, there have been only a few small studies in this area so we cannot yet say for sure.""
http://www.aicr.org.

uk/CannabisandCancer

.stm

""But claims that this body of preclinical research is solid “proof” that cannabis or cannabinoids can cure cancer is highly misleading to patients and their families, and builds a false picture of the state of progress in this area.""
http://scienceblog.c

ancerresearchuk.org/

2012/07/25/cannabis-

cannabinoids-and-can

cer-the-evidence-so-

far/
""There is some evidence that cannabis or cannabis derivatives might help with cancer symptoms and treatment side effects, for example, sickness caused by chemotherapy. However, there have been only a few small studies in this area so we cannot yet say for sure."" http://www.aicr.org. uk/CannabisandCancer .stm ""But claims that this body of preclinical research is solid “proof” that cannabis or cannabinoids can cure cancer is highly misleading to patients and their families, and builds a false picture of the state of progress in this area."" http://scienceblog.c ancerresearchuk.org/ 2012/07/25/cannabis- cannabinoids-and-can cer-the-evidence-so- far/ Dr Martin
  • Score: 0
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